Why has adult hippocampal neurogenesis had so little impact on psychiatry?
نویسندگان
چکیده
منابع مشابه
Adult Hippocampal Neurogenesis and Memory
Adult neurogenesis, a concept emergent in the late 1990s, is the generation of new neurons in the adult brain. This process occurs thank to cells who have this proliferative feature, named as Neural Stem Cells (NSCs). Neural Stem Cells (NSCs) are primary progenitors who can generate the two neural types (neurons and glia). Classically it was assumed that NSCs are only present in the embryo, but...
متن کاملAdult Hippocampal Neurogenesis and Memory
Adult neurogenesis, a concept emergent in the late 1990s, is the generation of new neurons in the adult brain. This process occurs thank to cells who have this proliferative feature, named as Neural Stem Cells (NSCs). Neural Stem Cells (NSCs) are primary progenitors who can generate the two neural types (neurons and glia). Classically it was assumed that NSCs are only present in the embryo, but...
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Swiprosin-1/Efhd2 (Efhd2) is highly expressed in the CNS during development and in the adult. EFHD2 is regulated by Ca2+ binding, stabilizes F-actin, and promotes neurite extension. Previous studies indicated a dysregulation of EFHD2 in human Alzheimer's disease brains. We hypothesized a detrimental effect of genetic ablation of Efhd2 on hippocampal integrity and specifically investigated adult...
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The dentate gyrus of the adult hippocampal formation generates neurons throughout life. To date, it remains unclear why. What are the new neurons used for? How can an existing functional neural network integrate and even actively recruit new neurons? The prevailing theories of cognition are based on the assumption that the adult brain is a stable network with regard to the number of neurons. In...
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ژورنال
عنوان ژورنال: The British Journal of Psychiatry
سال: 2018
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.2017.44